Publication & Citation Trends
Publications
0 total
SAR340835, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Cardiac Function and Restores Sympathovagal Balance in Heart Failure OA
Cited by 13
Semantic Scholar
SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models OA
Cited by 41
Semantic Scholar
Abstract 3070: Discovery of novel potent allele-selective KRAS-G12C covalent inhibitors stemming from DNA-encoded library
Cited by 0
Semantic Scholar
Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
Cited by 73
Semantic Scholar
Abstract 5775: Identification of SAR439859, an orally bioavailable selective estrogen receptor degrader (SERD) that has strong anti-tumor activity in wild-type and mutant ER+ breast cancer models
Cited by 0
Semantic Scholar
Abstract 943: SAR439859, an orally bioavailable selective estrogen receptor degrader (SERD) that demonstrates robust antitumor efficacy and limited cross-resistance in ER+ breast cancer
Cited by 7
Semantic Scholar
Discovery of (2S)-8-[(3R)-3-methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido[1,2-a]pyrimidin-6-one: a novel potent and selective inhibitor of Vps34 for the treatment of solid tumors. OA
Cited by 94
Semantic Scholar
The use of virtual screening and differential scanning fluorimetry for the rapid identification of fragments active against MEK1.
Cited by 27
Semantic Scholar
Crystal structure of MEK1 in complex with fragment 18
Cited by 0
Semantic Scholar
Research Topics
Estrogen and related hormone effects
(10)
Computational Drug Discovery Methods
(9)
Advanced Breast Cancer Therapies
(7)
Receptor Mechanisms and Signaling
(4)
Click Chemistry and Applications
(4)
Affiliations
Sanofi (France)
Sanofi (United States)
Smiths Detection (France)
Sanofi (Germany)
Sanofi (Turkey)