David T. Dudley

Independent Researcher

Publications

10,163

Citations

H-Index

i10-Index

2yr Mean Cite

Cite/Paper

Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar

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Publication & Citation Trends

Most Cited Works

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo OA

Dario R. Alessi, Ana Cuenda, Philip Cohen, David T. Dudley, Alan R. Saltiel

Journal of Biological Chemistry 1995

3,422

A synthetic inhibitor of the mitogen-activated protein kinase cascade. OA

David T. Dudley, Long Pang, Stuart J. Decker, Alexander J. Bridges, Alan R. Saltiel

Proceedings of the National Academy of Sciences 1995

2,705

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

Judith S. Sebolt–Leopold, David T. Dudley, Román Herrera, Keri Van Becelaere, Amy M. Wiland +7 more

Nature Medicine 1999

967

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Jeffrey F. Ohren, Huifen Chen, A.G. Pavlovsky, Christopher E. Whitehead, Erli Zhang +17 more

Nature Structural & Molecular Biology 2004

615

Subclasses of angiotensin II binding sites and their functional significance.

David T. Dudley, Robert L. Panek, Terry C. Major, Gina H. Lu, Robert F. Bruns +3 more

Molecular Pharmacology 1990

378

Publications

48 total

Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain PDF

Kay Ahn, Sarah E. Smith, Marya Liimatta, David Beidler, Nalini Sadagopan et al. - Journal of Pharmacology and Experimental Therapeutics, 2011

Cited by 230 OpenAlex

Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice PDF

Steven G. Kinsey, Pattipati S. Naidu, Benjamin F. Cravatt, David T. Dudley, Aron H. Lichtman - Pharmacology Biochemistry and Behavior, 2011

Cited by 84 OpenAlex

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor PDF

Douglas S. Johnson, Cory M. Stiff, Scott E. Lazerwith, Suzanne R. Kesten, Lorraine K. Fay et al. - ACS Medicinal Chemistry Letters, 2010

Cited by 196 OpenAlex

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901

Stephen D. Barrett, Alexander J. Bridges, David T. Dudley, Alan R. Saltiel, James H. Fergus et al. - Bioorganic & Medicinal Chemistry Letters, 2008

Cited by 283 OpenAlex

Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: Potential proinflammatory mechanisms PDF

Melissa Thiel, Caralee Schaefer, Mark E. Lesch, James L. Mobley, David T. Dudley et al. - Arthritis & Rheumatism, 2007

Cited by 100 OpenAlex

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Jeffrey F. Ohren, Huifen Chen, A.G. Pavlovsky, Christopher E. Whitehead, Erli Zhang et al. - Nature Structural & Molecular Biology, 2004

Cited by 615 OpenAlex

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

Judith S. Sebolt–Leopold, David T. Dudley, Román Herrera, Keri Van Becelaere, Amy M. Wiland et al. - Nature Medicine, 1999

Cited by 967 OpenAlex

PD98059 Is an Equipotent Antagonist of the Aryl Hydrocarbon Receptor and Inhibitor of Mitogen-Activated Protein Kinase Kinase

John J. Reiners, Jing‐Yu Lee, Russell E. Clift, David T. Dudley, Scott P. Myrand - Molecular Pharmacology, 1998

Cited by 147 OpenAlex

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo PDF

Dario R. Alessi, Ana Cuenda, Philip Cohen, David T. Dudley, Alan R. Saltiel - Journal of Biological Chemistry, 1995

Cited by 3,422 OpenAlex

A synthetic inhibitor of the mitogen-activated protein kinase cascade. PDF

David T. Dudley, Long Pang, Stuart J. Decker, Alexander J. Bridges, Alan R. Saltiel - Proceedings of the National Academy of Sciences, 1995

Cited by 2,705 OpenAlex

Research Topics

Melanoma and MAPK Pathways (11) Receptor Mechanisms and Signaling (8) Nitric Oxide and Endothelin Effects (4) Protein Kinase Regulation and GTPase Signaling (4) Fatty Acid Research and Health (4)

Frequent Co-Authors

Alan R. Saltiel

4 joint publications

Haile Tecle

4 joint publications

Stephen D. Barrett

4 joint publications

Alexander J. Bridges

3 joint publications

Judith S. Sebolt–Leopold

3 joint publications

Keri Van Becelaere

3 joint publications

Affiliations

University of Iowa

US 1988 - 1979

Gaertner (United States)

US 1999 - 1993

Université de Sherbrooke

CA 1994 - 1994

Pfizer (United States)

US 2011 - 2001

Wayne State University

US 1998 - 1998

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David T. Dudley

Publication & Citation Trends

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