Anthony Ivetac
0000-0002-4174-6605
Publication & Citation Trends
Publications
0 total
Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein OA
Cited by 11
Semantic Scholar
The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading OA
Cited by 19
Semantic Scholar
Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography OA
Cited by 7
Semantic Scholar
Abstract LB505: Design and discovery of MRTX0902, a potent, selective, and orally bioavailable SOS1 inhibitor
Cited by 0
Semantic Scholar
Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors.
Cited by 11
Semantic Scholar
Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein–Protein Interaction OA
Cited by 73
Semantic Scholar
Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP-Deleted Cancers. OA
Cited by 113
Semantic Scholar
Fragment optimization and elaboration strategies – the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits OA
Cited by 3
Semantic Scholar
Research Topics
ATP Synthase and ATPases Research
(16)
Biochemical and Molecular Research
(16)
Cytokine Signaling Pathways and Interactions
(14)
Protein Structure and Dynamics
(8)
DNA and Nucleic Acid Chemistry
(6)
Affiliations
Howard Hughes Medical Institute
University of Trieste
Oregon Health & Science University
Schrodinger (United States)
University of California San Diego