Eric D. Spear
0000-0003-1980-0123
Publication & Citation Trends
Most Cited Works
Publications
28 total
The zinc metalloprotease ZMPSTE24 binds a distinct topological isoform of the tail-anchored protein IFITM3
Cited by 0
Semantic Scholar
Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice PDF
Cited by 17
OpenAlex
Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control OA
Cited by 8
Semantic Scholar
The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia Formation OA
Cited by 13
Semantic Scholar
Site specificity determinants for prelamin A cleavage by the zinc metalloprotease ZMPSTE24 PDF
Cited by 21
OpenAlex
Cleavage Site Specificity for Processing of Farnesylated Prelamin A by the Zinc Metalloprotease ZMPSTE24 OA
Cited by 1
Semantic Scholar
A new paradigm for Prelamin A proteolytic processing by ZMPSTE24: the upstream SY^LL cleavage occurs first and there is no CaaX processing by ZMPSTE24 OA
Cited by 7
Semantic Scholar
Defining substrate requirements for cleavage of farnesylated prelamin A by the integral membrane zinc metalloprotease ZMPSTE24 OA
Cited by 5
Semantic Scholar
A humanized yeast system to analyze cleavage of prelamin A by ZMPSTE24. OA
Cited by 14
Semantic Scholar
Research Topics
Nuclear Structure and Function
(14)
RNA Research and Splicing
(11)
Endoplasmic Reticulum Stress and Disease
(8)
Cellular transport and secretion
(7)
Genomics and Chromatin Dynamics
(5)
Frequent Co-Authors
Affiliations
Argonne National Laboratory
Pennsylvania State University
Johns Hopkins University
University of Toronto
Johns Hopkins Medicine