Michael S. Wolfe
0000-0002-5721-9092
Publication & Citation Trends
Publications
0 total
Molecular Dynamics Activation of γ-Secretase for Cleavage of Notch1 Substrate OA
Cited by 5
Semantic Scholar
Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half‐life OA
Cited by 27
Semantic Scholar
P2-378 COMBINATION THERAPY FOR ALZHEIMER’S DISEASE: MEMANTINE AND CHOLINESTERASE INHIBITORS
Cited by 12
Semantic Scholar
P1‐218: A NOVEL CELLULAR COMPLEX OF BACE1 AND γ‐SECRETASE SEQUENTIALLY GENERATES Aβ FROM APP OA
Cited by 0
Semantic Scholar
P4‐071: The Amyloid‐B Generating Tri‐Peptide Cleavage Mechanism of Gamma‐Secretase: Implications for Alzheimer's Disease OA
Cited by 3
Semantic Scholar
P4‐221: Nicastrin functions as a molecular gatekeeper to a high‐affinity γ‐secretase‐substrate interaction driven by substrate transmembrane domain
Cited by 3
Semantic Scholar
P1‐082: Investigation of substrate determinants for proteolysis of app ctfβ by gamma‐secretase OA
Cited by 0
Semantic Scholar
S2‐03‐01: Splicing and dicing in APP processing: Targeting proteases and mRNAs that regulate A‐beta production OA
Cited by 0
Semantic Scholar
Substrate-targeting γ-secretase modulators
Cited by 0
Semantic Scholar
P2‐338: Substrate‐targeting gamma‐secretase modulators OA
Cited by 85
Semantic Scholar
Research Topics
Alzheimer's disease research and treatments
(144)
Cholinesterase and Neurodegenerative Diseases
(36)
Computational Drug Discovery Methods
(31)
Cellular transport and secretion
(25)
Supramolecular Self-Assembly in Materials
(24)
Affiliations
Queens College, CUNY
Oklahoma State University
Scripps Research Institute
Brigham and Women's Hospital
National Institutes of Health