Helmut Jacobsen
0000-0002-8832-8021
Publication & Citation Trends
Publications
0 total
RO6807936 as a Novel PET Radiotracer for in Vitro and in Vivo Visualization and Quantification of BACE1 in the Rodent and Baboon Brain.
Cited by 1
Semantic Scholar
of GSMs affect Nß-and Aß-profile modulation, we will get more insights into the mode of action of this new class of promising g-secretase modulat- ing compounds. P2-318 BIOLOGICAL CONSEQUENCES OF BACE1- DEPENDENT PROCESSING OF NEUREGULIN
Cited by 8
Semantic Scholar
A subcutaneous cellular implant for passive immunization against amyloid-β reduces brain amyloid and tau pathologies. OA
Cited by 35
Semantic Scholar
Cargo Delivery into the Brain by in vivo identified Transport Peptides OA
Cited by 43
Semantic Scholar
Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation.
Cited by 16
Semantic Scholar
Combined Treatment with a BACE Inhibitor and Anti-Aβ Antibody Gantenerumab Enhances Amyloid Reduction in APPLondon Mice OA
Cited by 92
Semantic Scholar
β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.
Cited by 114
Semantic Scholar
BACE1 inhibitors: a head group scan on a series of amides.
Cited by 49
Semantic Scholar
Research Topics
Alzheimer's disease research and treatments
(28)
Cholinesterase and Neurodegenerative Diseases
(14)
Nuclear Receptors and Signaling
(12)
Monoclonal and Polyclonal Antibodies Research
(11)
HIV Research and Treatment
(10)
Affiliations
Roche (Switzerland)
Novartis (Switzerland)
Health Canada
Roche (United States)
National Institutes of Health