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DL

Daniel C.-H. Lin

West Virginia University US

36
Publications
2,962
Citations
23
H-Index
27
i10-Index
0
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Most Cited Works

Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors OA
Weihai He, Frederick Jia‐Pei Miao, Daniel C.-H. Lin, Ralf Schwandner, Zhulun Wang +4 more
Nature 2004
885
GPR40 Is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion In Vivo OA
Martin G. Latour, Thierry Alquier, Elizabeth Oseid, Caroline Tremblay, Thomas L. Jetton +3 more
Diabetes 2007
261
A Potent Class of GPR40 Full Agonists Engages the EnteroInsular Axis to Promote Glucose Control in Rodents OA
Jian Luo, Gayathri Swaminath, Sean P. Brown, Jane Zhang, Qi Guo +13 more
PLoS ONE 2012
136
AMG 837: A potent, orally bioavailable GPR40 agonist OA
Jonathan B. Houze, Liusheng Zhu, Ying Sun, Michelle Akerman, Wei Qiu +20 more
Bioorganic & Medicinal Chemistry Letters 2011
130
A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery OA
Tracy Tran, Cheng Song, Trang Nguyen, Shun-Yang Cheng, Jill A. McMahon +6 more
Cell stem cell 2022
124

Publications

36 total

A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery PDF

Tracy Tran, Cheng Song, Trang Nguyen, Shun-Yang Cheng, Jill A. McMahon et al. - Cell stem cell, 2022
Cited by 124 OpenAlex

Structural basis for pharmacological modulation of the TRPC6 channel PDF

Yonghong Bai, Xinchao Yu, Hao Chen, Daniel B. Horne, Ryan D. White et al. - eLife, 2020
Cited by 115 OpenAlex

Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1

Yumei Xiong, Gayathri Swaminath, Qiong Cao, Li Yang, Qi Guo et al. - Molecular and Cellular Endocrinology, 2013
Cited by 89 OpenAlex

Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles PDF

Yingcai Wang, Jiwen Liu, Paul J. Dransfield, Liusheng Zhu, Zhongyu Wang et al. - ACS Medicinal Chemistry Letters, 2013
Cited by 81 OpenAlex

A Potent Class of GPR40 Full Agonists Engages the EnteroInsular Axis to Promote Glucose Control in Rodents PDF

Jian Luo, Gayathri Swaminath, Sean P. Brown, Jane Zhang, Qi Guo et al. - PLoS ONE, 2012
Cited by 136 OpenAlex

Identification and Pharmacological Characterization of Multiple Allosteric Binding Sites on the Free Fatty Acid 1 Receptor PDF

Daniel C.-H. Lin, Qi Guo, Jian Luo, Jane Zhang, Kathy Nguyen et al. - Molecular Pharmacology, 2012
Cited by 119 OpenAlex

Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist PDF

Sean P. Brown, Paul J. Dransfield, Marc Vimolratana, Xian‐Yun Jiao, Liusheng Zhu et al. - ACS Medicinal Chemistry Letters, 2012
Cited by 89 OpenAlex

AMG 837: A potent, orally bioavailable GPR40 agonist PDF

Jonathan B. Houze, Liusheng Zhu, Ying Sun, Michelle Akerman, Wei Qiu et al. - Bioorganic & Medicinal Chemistry Letters, 2011
Cited by 130 OpenAlex

AMG 837: A Novel GPR40/FFA1 Agonist that Enhances Insulin Secretion and Lowers Glucose Levels in Rodents PDF

Daniel C.-H. Lin, Jane Zhang, Run Zhuang, Frank Li, Kathy Nguyen et al. - PLoS ONE, 2011
Cited by 94 OpenAlex

GPR40 Is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion In Vivo PDF

Martin G. Latour, Thierry Alquier, Elizabeth Oseid, Caroline Tremblay, Thomas L. Jetton et al. - Diabetes, 2007
Cited by 261 OpenAlex

Research Topics

Diabetes Treatment and Management (14) Receptor Mechanisms and Signaling (13) Pancreatic function and diabetes (8) Neurotransmitter Receptor Influence on Behavior (7) Neuropeptides and Animal Physiology (5)

Frequent Co-Authors

JI
Jian Luo
7 joint publications
JA
Jane Zhang
7 joint publications
JO
Jonathan B. Houze
7 joint publications
GA
Gayathri Swaminath
6 joint publications
PA
Paul J. Dransfield
5 joint publications
SE
Sean P. Brown
4 joint publications

Affiliations

West Virginia University
US 2025 - 2025
Scripps Research Institute
US 2003 - 1999
Scripps Health
US 2002 - 2002
Amgen (United States)
US 2022 - 2007
Oregon Health & Science University
US 2005 - 1998

External Profiles

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