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The trans-ancestral genomic architecture of glycemic traits

Jihua Chen, Cassandra N. Spracklen, Gaëlle Marenne, Arushi Varshney, Laura J. Corbin, Jian’an Luan, Sara M. Willems, Ying Wu, Xiaoshuai Zhang, Momoko Horikoshi, Thibaud Boutin, Reedik Mägi, Johannes Waage, Ruifang Li‐Gao, Kei Hang Katie Chan, Jie Yao, Mila Desi Anasanti, Audrey Y. Chu, Annique Claringbould, Jani Heikkinen, Jaeyoung Hong, Jouke‐Jan Hottenga, Shaofeng Huo, Marika Kaakinen, Tin Louie, Winfried März, Hortensia Moreno-Macías, Anne Ndungu, Sarah C. Nelson, Ilja M. Nolte, Kari E. North, Chelsea K. Raulerson, Debashree Ray, Rebecca Rohde, Denis Rybin, Claudia Schurmann, Xueling Sim, Lorraine Southam, Isobel D. Stewart, Carol A. Wang, Yujie Wang, Peitao Wu, Weihua Zhang, Tarunveer S. Ahluwalia, Emil V. R. Appel, Lawrence F. Bielak, Jennifer A. Brody, Noël P. Burtt, Claudia Cabrera, Brian E. Cade, Jin Fang Chai, Xiaoran Chai, Li-Ching Chang, Chien-Hsiun Chen, Brian H. Chen, Kumaraswamy Naidu Chitrala, Yen‐Feng Chiu, Hugoline G. de Haan, Graciela E. Delgado, Ayşe Demirkan, Qing Duan, Jorgen Engmann, Segun Fatumo, Javier Gayán, Franco Giulianini, Jung Ho Gong, Stefan Gustafsson, Yang Hai, Fernando Pires Hartwig, Jing He, Yoriko Heianza, Tao Huang, Alicia Huerta‐Chagoya, Mi Yeong Hwang, Richard A. Jensen, Takahisa Kawaguchi, Katherine A. Kentistou, Young Jin Kim, Marcus E. Kleber, Ishminder K. Kooner, Shuiqing Lai, Leslie A. Lange, Carl D. Langefeld, Marie Lauzon, Man Li, Symen Ligthart, Jun Liu, Marie Loh, Jirong Long, Valeriya Lyssenko, Massimo Mangino, Carola Marzi, May E. Montasser, Abhishek Nag, Masahiro Nakatochi, Damia Noce, Raymond Noordam, Giorgio Pistis, Michael Preuß, Laura M. Raffield, Laura J. Rasmussen‐Torvik, Stephen S. Rich, Neil R. Robertson, Rico Rueedi, Kathleen A. Ryan, Serena Sanna, Richa Saxena, Katharina E. Schraut, Bengt Sennblad, Kazuya Setoh, Albert V. Smith, Thomas Sparsø, Rona J. Strawbridge, Fumihiko Takeuchi, Jingyi Tan, Stella Trompet, Erik B. van den Akker, Peter J. van der Most, Niek Verweij, Mandy Vogel, Heming Wang, Chaolong Wang, Nan Wang, Helen R. Warren, Wanqing Wen, Tom Wilsgaard, Andrew Wong, Andrew R. Wood, Tian Xie, Mohammad Hadi Zafarmand, Jinghua Zhao, Wei Zhao, Najaf Amin, Zorayr Arzumanyan, Arne Astrup, Stephan J. L. Bakker, Damiano Baldassarre, Marian Beekman, Richard N. Bergman, Alain G. Bertoni, Matthias Blüher, Lori L. Bonnycastle, Stefan R. Bornstein, Donald W. Bowden, Qiuyin Cai, Archie Campbell, Harry Campbell, Yi‐Cheng Chang, Eco J. C. de Geus, Abbas Dehghan, Shufa Du, Guðný Eiríksdóttir, Aliki Eleni Farmaki, Mattias Frånberg, Christian Fuchsberger, Yu‐Tang Gao, Anette P. Gjesing, Anuj Goel, Sohee Han, Catharina A. Hartman, Christian Herder, Andrew A. Hicks, Chang‐Hsun Hsieh, Willa A. Hsueh, Sahoko Ichihara, Michiya Igase, M. Arfan Ikram, W. Craig Johnson, Marit E. Jørgensen, Peter K. Joshi, Rita R. Kalyani, Fouad Kandeel, Tomohiro Katsuya, Chiea Chuen Khor, Wieland Kieß, Ivana Kolčić, Teemu Kuulasmaa, Johanna Kuusisto, Kristi Läll, Kelvin Lam, Debbie A. Lawlor, Sang Lee, Rozenn N. Lemaître, Honglan Li, Lifelines Cohort Study, Shih-Yi Lin, Jaana Lindström, Allan Linneberg, Jianjun Liu, Carlos Lorenzo, Tatsuaki Matsubara, Fumihiko Matsuda, Geltrude Mingrone, Simon P. Mooijaart, Sanghoon Moon, Toru Nabika, Girish N. Nadkarni, Jerry L. Nadler, Mari Nelis, Matt J. Neville, Jill M. Norris, Yasumasa Ohyagi, Annette Peters, Patricia A. Peyser, Ozren Polašek, Qibin Qi, Dennis Raven, Dermot F. Reilly, Alex P. Reiner, Fernando Rivideneira, Kathryn Roll, Igor Rudan, Charumathi Sabanayagam, Kevin Sandow, Naveed Sattar, Annette Schürmann, Jinxiu Shi, Heather M. Stringham, Kent D. Taylor, Tanya M. Teslovich, Betina H. Thuesen, Paul R. H. J. Timmers, Elena Tremoli, Michael Y. Tsai, André G. Uitterlinden, Rob M. van Dam, Diana van Heemst, Astrid van Hylckama Vlieg, Jana V. van Vliet‐Ostaptchouk, Jagadish Vangipurapu, Henrik Vestergaard, Tao Wang, Ko Willems van Dijk, Tatijana Zemunik, Gonçalo R. Abecasis, Linda S. Adair, Carlos A. Aguilar‐Salinas, Marta E. Alarcón‐Riquelme, Ping An, Larissa Avilés‐Santa, Diane M. Becker, Lawrence J. Beilin, Sven Bergmann, Hans Bisgaard, Corri Black, Michael Boehnke, Eric Boerwinkle, Bernhard Böhm, Klaus Bønnelykke, Dorret I. Boomsma, Erwin P. Böttinger, Thomas A. Buchanan, Mickaël Canouil, Mark J. Caulfield, John C. Chambers, Daniel I. Chasman, Yii‐Der Ida Chen, Ching‐Yu Cheng, Francis S. Collins, Adolfo Correa, Francesco Cucca, H. Janaka de Silva, George Dedoussis, Sölve Elmståhl, Michele K. Evans, Ele Ferrannini, Luigi Ferrucci, José C. Florez, Paul W. Franks, Timothy M. Frayling, Philippe Froguel, Bruna Gigante, Mark O. Goodarzi, Penny Gordon‐Larsen, Harald Grallert, Niels Grarup, Sameline Grimsgaard, Leif Groop, Vilmundur Guðnason, Xiuqing Guo, Anders Hamsten, Torben Hansen, Caroline Hayward, Susan R. Heckbert, Bernardo Lessa Horta, Wei Huang, Erik Ingelsson, James S. Pankow, Marjo‐Riitta Järvelin, Jost B. Jonas, J. Wouter Jukema, Pontiano Kaleebu, Robert S. Kaplan, Sharon L. R. Kardia, Norihiro Kato, Sirkka Keinänen‐Kiukaanniemi, Bong-Jo Kim, Mika Kivimäki, Heikki A. Koistinen, Jaspal S Kooner, Antje Körner, Péter Kovács, Diana Kuh, Meena Kumari, Zoltán Kutalik, Markku Laakso, Timo A. Lakka, Lenore J. Launer, Karin Leander, Huaixing Li, Lin Xu, Lars Lind, Cecilia M. Lindgren, Simin Liu, Ruth J. F. Loos, Patrik K. E. Magnusson, Anubha Mahajan, Andres Metspalu, Dennis O. Mook‐Kanamori, Trevor A. Mori, Patricia B. Munroe, Inger Njølstad, Jeffrey R. O’Connell, Albertine J. Oldehinkel, Ken K. Ong, Sandosh Padmanabhan, Colin N. A. Palmer, Nicholette D. Palmer, Oluf Pedersen, Craig E. Pennell, David J. Porteous, Peter P. Pramstaller, Michael A. Province, Bruce M. Psaty, Lu Qi, Leslie J. Raffel, Rainer Rauramaa, Susan Redline, Paul M. Ridker, Frits R. Rosendaal, Timo Saaristo, Manjinder S. Sandhu, Jouko Saramies, Neil Schneiderman, Peter E. H. Schwarz, Laura J. Scott, Elizabeth Selvin, Peter Sever, Xiao‐Ou Shu, P. Eline Slagboom, Kerrin S. Small, Blair H. Smith, Harold Snieder, Tamar Sofer, Thorkild I. A. Sørensen, Tim D Spector, Alice Stanton, Claire J. Steves, Michael Stümvoll, Liang Sun, Yasuharu Tabara, E Shyong Tai, Nicholas J. Timpson, Anke Tönjes, Jaakko Tuomilehto, Teresa Tusié, Matti Uusitupa, Pim van der Harst, Cornelia M. van Duijn, Véronique Vitart, Péter Vollenweider, Tanja G. M. Vrijkotte, Lynne E. Wagenknecht, Mark Walker, Ya X. Wang, Nicholas J. Wareham, Richard M. Watanabe, Hugh Watkins, Wen Bin Wei, Ananda R. Wickremasinghe, Gonneke Willemsen, James F. Wilson, Tien Yin Wong, Jer‐Yuarn Wu, Anny H. Xiang, Lisa R. Yanek, Loïc Yengo, Mitsuhiro Yokota, Eleftheria Zeggini, Wei Zheng, Alan B Zonderman, Jerome I. Rotter, Anna L. Gloyn, Mark I. McCarthy, Josée Dupuis, James B. Meigs, Robert A. Scott, Inga Prokopenko, Aaron Leong, Ching‐Ti Liu, Stephen C.J. Parker, Karen L. Mohlke, Claudia Langenberg, Eleanor Wheeler, Andrew P. Morris, Inês Barroso, Hugoline G. de Haan, Erik B. van den Akker, Peter J. van der Most, Eco J. C. de Geus, Rob M. van Dam, Diana van Heemst, Astrid van Hylckama Vlieg, Ko Willems van Dijk, H. Janaka de Silva, Pim van der Harst, Cornelia M. van Duijn

Nature Genetics, 2021

University of Exeter, Wellcome Sanger Institute, University of North Carolina at Chapel Hill, University of Massachusetts Amherst, Inserm, Université de Bretagne Occidentale, École nationale d'ingénieurs de Brest, University of Michigan, University of Bristol, MRC Epidemiology Unit, University of Cambridge, Shandong University, Centre for Human Genetics, University of Oxford, Oxford Centre for Diabetes, Endocrinology and Metabolism, RIKEN Center for Integrative Medical Sciences, Institute of Genetics and Cancer, MRC Human Genetics Unit, Medical Research Council, University of Tartu, University of Copenhagen, Gentofte Hospital, Copenhagen Prospective Studies on Asthma in Childhood, Leiden University Medical Center, City University of Hong Kong, Brown University, UCLA Medical Center, Harbor–UCLA Medical Center, Imperial College London, Brigham and Women's Hospital, University Medical Center Groningen, University of Groningen, Boston University, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, University of Surrey, University of Washington, Medical University of Graz, Heidelberg University, University Hospital Heidelberg, Synlab (Germany), University Medical Centre Mannheim, Universidad Autónoma Metropolitana, Johns Hopkins University, Hasso Plattner Institute, Icahn School of Medicine at Mount Sinai, National University Health System, Helmholtz Zentrum München, Agency for Science, Technology and Research, Huazhong University of Science and Technology, Genome Institute of Singapore, University of Newcastle Australia, Beijing Tongren Hospital, Capital Medical University, Ealing Hospital, London North West Healthcare NHS Trust, Steno Diabetes Centers, Novo Nordisk Foundation, Broad Institute, Queen Mary University of London, William Harvey Research Institute, Harvard University, Circadian (United States), National University of Singapore, Singapore National Eye Center, Singapore Eye Research Institute, Institute of Biomedical Sciences, Academia Sinica, University of California San Diego, Human Longevity (United States), National Institutes of Health, National Institute on Aging, National Health Research Institutes, Erasmus MC, University College London, London School of Hygiene & Tropical Medicine, African Field Epidemiology Network, Uganda Virus Research Institute, Uppsala University, Science for Life Laboratory, University of Auckland, Universidade Federal de Pelotas, Vanderbilt University Medical Center, Tulane University, Peking University, National Institute of Genomic Medicine, Secretaría de Ciencia, Humanidades, Tecnología e Innovación, Korea National Institute of Health, Kyoto University, The Queen's Medical Research Institute, University of Edinburgh, University of Colorado Anschutz Medical Campus, Wake Forest University, University of Utah, Nanyang Technological University, Lund University, University of Bergen, King's College London, Guy's and St Thomas' NHS Foundation Trust, Deutsches Diabetes-Zentrum e.V., German Center for Diabetes Research, Heinrich Heine University Düsseldorf, University of Maryland, Baltimore, Nagoya University, Eurac Research, Institute for Biomedicine, Institute of Genetic and Biomedical Research, Child Health and Development Institute, Northwestern University, University of Virginia, SIB Swiss Institute of Bioinformatics, University of Lausanne, Massachusetts General Hospital, Icelandic Heart Association, Karolinska Institutet, University of Glasgow, National Center for Global Health and Medicine, Delft University of Technology, Genomics (United Kingdom), University Hospital Leipzig, Leipzig University, University of Southern California, UiT The Arctic University of Norway, MRC Unit for Lifelong Health and Ageing, GGD Amsterdam, University of Amsterdam, University of Milan, Centro Cardiologico Monzino, Cedars-Sinai Medical Center, National Human Genome Research Institute, University Hospital Carl Gustav Carus, Technische Universität Dresden, Western General Hospital, National Taiwan University, National Taiwan University Hospital, Harokopio University of Athens, Shanghai Cancer Institute, Tri-Service General Hospital, National Defense Medical Center, The Ohio State University Wexner Medical Center, Jichi Medical University, Ehime University, University of Southern Denmark, Johns Hopkins Medicine, City of Hope, Beckman Research Institute, The University of Osaka, University of Split, University of Eastern Finland, Kuopio University Hospital, Foundation University, University of San Carlos, Renji Hospital, State Key Laboratory of Oncogene and Related Genes, National Yang Ming Chiao Tung University, Taichung Veterans General Hospital, Finnish Institute for Health and Welfare, Frederiksberg Hospital, Center for Clinical Research and Prevention, The University of Texas at San Antonio Health Science Center, Aichi Gakuin University, Shimane University, New York Medical College, Oxford BioMedica (United Kingdom), Colorado School of Public Health, Zimmer Biomet (Germany), Ludwig-Maximilians-Universität München, Albert Einstein College of Medicine, Merck & Co., Inc., Rahway, NJ, USA (United States), Fred Hutch Cancer Center, Duke-NUS Medical School, German Institute of Human Nutrition, Chinese National Human Genome Center, Chinese National Human Genome Center at Shanghai, Shanghai Academy of Science & Technology, Sarepta Therapeutics (United States), University of Minnesota, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tecnológico de Monterrey, Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research, Washington University in St. Louis, National Institute on Minority Health and Health Disparities, The University of Western Australia, Royal Perth Hospital, University of Cape Town, University of Aberdeen, Baylor College of Medicine, The University of Texas Health Science Center at Houston, Universität Ulm, Centre National de la Recherche Scientifique, Université de Lille, European Genomic Institute for Diabetes, Imperial College Healthcare NHS Trust, Jackson Memorial Hospital, University of Mississippi Medical Center, University of Kelaniya, Istituto di Fisiologia Clinica, Umeå University, Genomics England, Institute for Molecular Medicine Finland, University of Iceland, Stanford University, Oulu University Hospital, Brunel University of London, University of Oulu, Institute of Molecular and Clinical Ophthalmology Basel, Netherlands Heart Institute, University of Helsinki, Helsinki University Hospital, Minerva Foundation, IFB Adiposity Diseases, University of Essex, Institute for Social and Economic Research, Open Data Institute, University of Dundee, Ninewells Hospital, University of California, Irvine, Finnish Diabetes Association, Pirkanmaa Hospital District, South Karelia Central Hospital, University of Miami, Paul Langerhans Institute Dresden, Royal College of Surgeons in Ireland, Signature Research (United States), King Abdulaziz University, Universidad Nacional Autónoma de México, Newcastle University, Kaiser Permanente, The University of Queensland, Kurume University, TUM Klinikum, Technical University of Munich, Stanford Medicine, University of Liverpool, University of Manchester, NIHR Oxford Musculoskeletal Biomedical Research Centre, Arthritis UK

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