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HE

Hassan Elokdah

Independent Researcher

27
Publications
920
Citations
14
H-Index
15
i10-Index
0
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Most Cited Works

Tiplaxtinin, a Novel, Orally Efficacious Inhibitor of Plasminogen Activator Inhibitor-1:  Design, Synthesis, and Preclinical Characterization OA
Hassan Elokdah, Magid Abou‐Gharbia, James K. Hennan, Geraldine McFarlane, Cheryl P. Mugford +2 more
Journal of Medicinal Chemistry 2004
167
Enhanced clearance of Aβ in brain by sustaining the plasmin proteolysis cascade OA
J. Steven Jacobsen, Thomas A. Comery, Robert Martone, Hassan Elokdah, David L. Crandall +21 more
Proceedings of the National Academy of Sciences 2008
140
Pharmacological Inhibition and Genetic Deficiency of Plasminogen Activator Inhibitor-1 Attenuates Angiotensin II/Salt-Induced Aortic Remodeling
Alec D. Weisberg, Francisco Albornoz, Jane P. Griffin, David L. Crandall, Hassan Elokdah +3 more
Arteriosclerosis Thrombosis and Vascular Biology 2004
109
Mechanism of Inactivation of Plasminogen Activator Inhibitor-1 by a Small Molecule Inhibitor OA
Natalia Gorlatova, Jacqueline M. Cale, Hassan Elokdah, Donghua Li, Kristi Fan +3 more
Journal of Biological Chemistry 2007
101
Pivotal role of PAI-1 in a murine model of hepatic vein thrombosis OA
Layton H. Smith, John D. Dixon, John R. Stringham, Mesut Eren, Hassan Elokdah +3 more
Blood 2005
59

Publications

27 total

Enhanced clearance of Aβ in brain by sustaining the plasmin proteolysis cascade PDF

J. Steven Jacobsen, Thomas A. Comery, Robert Martone, Hassan Elokdah, David L. Crandall et al. - Proceedings of the National Academy of Sciences, 2008
Cited by 140 OpenAlex

Efficient one-pot synthesis of substituted 2-amino-1,3,4-oxadiazoles

Eugene L. Piatnitski Chekler, Hassan Elokdah, John A. Butera - Tetrahedron Letters, 2008
Cited by 37 OpenAlex

Dose-dependent thrombus resolution due to oral plasminogen activator inhibitor (PAI)-1 inhibition with tiplaxtinin in a rat stenosis model of venous thrombosis

Sanjiv M. Baxi, David L. Crandall, Thomas Meier, Shirley K. Wrobleski, Angela E. Hawley et al. - Thrombosis and Haemostasis, 2008
Cited by 28 OpenAlex

Mechanism of Inactivation of Plasminogen Activator Inhibitor-1 by a Small Molecule Inhibitor PDF

Natalia Gorlatova, Jacqueline M. Cale, Hassan Elokdah, Donghua Li, Kristi Fan et al. - Journal of Biological Chemistry, 2007
Cited by 101 OpenAlex

Neutralization of Plasminogen Activator Inhibitor I (PAI-1) by the Synthetic Antagonist PAI-749 via a Dual Mechanism of Action

Stephen J. Gardell, Julie A. Krueger, Thomas A Antrilli, Hassan Elokdah, Scott C. Mayer et al. - Molecular Pharmacology, 2007
Cited by 28 OpenAlex

Novel 1-(azacyclyl)-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines as 5-HT6 agonists and antagonists PDF

Hassan Elokdah, David Li, Geraldine McFarlane, Ronald C. Bernotas, Albert J. Robichaud et al. - Bioorganic & Medicinal Chemistry, 2007
Cited by 14 OpenAlex

Regioselective Suzuki coupling of benzofuran or benzothiophene boronic acids and dibromo substituted naphthalenes: synthesis of a potent inhibitor of plasminogen activator inhibitor-1

Zheng Wang, Hassan Elokdah, Geraldine McFarlane, Sherry Pan, Madelene Antane - Tetrahedron Letters, 2006
Cited by 30 OpenAlex

Pivotal role of PAI-1 in a murine model of hepatic vein thrombosis PDF

Layton H. Smith, John D. Dixon, John R. Stringham, Mesut Eren, Hassan Elokdah et al. - Blood, 2005
Cited by 59 OpenAlex

Evaluation of PAI-039 [{1-Benzyl-5-[4-(trifluoromethoxy)phenyl]-1 H-indol-3-yl}(oxo)acetic Acid], a Novel Plasminogen Activator Inhibitor-1 Inhibitor, in a Canine Model of Coronary Artery Thrombosis

James K. Hennan, Hassan Elokdah, Mauricio Leal, Allena Ji, Gregory S. Friedrichs et al. - Journal of Pharmacology and Experimental Therapeutics, 2005
Cited by 42 OpenAlex

Tiplaxtinin, a Novel, Orally Efficacious Inhibitor of Plasminogen Activator Inhibitor-1:  Design, Synthesis, and Preclinical Characterization PDF

Hassan Elokdah, Magid Abou‐Gharbia, James K. Hennan, Geraldine McFarlane, Cheryl P. Mugford et al. - Journal of Medicinal Chemistry, 2004
Cited by 167 OpenAlex

Research Topics

Protease and Inhibitor Mechanisms (13) Blood Coagulation and Thrombosis Mechanisms (7) Synthesis and Reactions of Organic Compounds (4) Synthesis and biological activity (3) Pharmacogenetics and Drug Metabolism (2)

Frequent Co-Authors

DA
David L. Crandall
10 joint publications
JA
James K. Hennan
4 joint publications
GE
Geraldine McFarlane
4 joint publications
MA
Magid Abou‐Gharbia
3 joint publications
NA
Natalia Gorlatova
3 joint publications
DA
Daniel A. Lawrence
3 joint publications

Affiliations

Pfizer (United States)
US 2008 - 2008
Princeton University
US 2006 - 2000
National Center for Drug Screening
CN 2008 - 2008
Women's Health Research Institute
CA 2007 - 2001
CNS Research (United States)
US 2001 - 2001

External Profiles

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