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LC

Lynne Chantranupong

Howard Hughes Medical Institute US

ORCID iD 0000-0001-9814-5264
47
Publications
7,834
Citations
22
H-Index
28
i10-Index
17.67
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Most Cited Works

A unifying model for mTORC1-mediated regulation of mRNA translation OA
Carson C. Thoreen, Lynne Chantranupong, Heather R. Keys, Timothy C. Wang, Nathanael S. Gray +1 more
Nature 2012
1,482
Sestrin2 is a leucine sensor for the mTORC1 pathway OA
Rachel L. Wolfson, Lynne Chantranupong, Robert A. Saxton, Kuang Shen, Sonia M. Scaria +2 more
Science 2015
1,249
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. OA
Shuyu Wang, Zhi-Yang Tsun, Rachel L. Wolfson, Kuang Shen, Gregory A. Wyant +13 more
PubMed 2015
814
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway OA
Lynne Chantranupong, Sonia M. Scaria, Robert A. Saxton, Melanie P. Gygi, Kuang Shen +5 more
Cell 2016
788
The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1 OA
Zhi-Yang Tsun, Liron Bar‐Peled, Lynne Chantranupong, Roberto Zoncu, Timothy C. Wang +3 more
Molecular Cell 2013
536

Publications

47 total

Dopamine and glutamate regulate striatal acetylcholine in decision-making PDF

Lynne Chantranupong, Celia Beron, Joshua A. Zimmer, Michelle J. Wen, Wengang Wang et al. - Nature, 2023
Cited by 149 OpenAlex

Architecture of the human GATOR1 and GATOR1–Rag GTPases complexes

Kuang Shen, Rick Huang, Edward J. Brignole, Kendall J. Condon, Max L. Valenstein et al. - Nature, 2018
Cited by 184 OpenAlex

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1 PDF

Rachel L. Wolfson, Lynne Chantranupong, Gregory A. Wyant, Xin Gu, Jose M. Orozco et al. - Nature, 2017
Cited by 318 OpenAlex

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway PDF

Lynne Chantranupong, Sonia M. Scaria, Robert A. Saxton, Melanie P. Gygi, Kuang Shen et al. - Cell, 2016
Cited by 788 OpenAlex

Mechanism of arginine sensing by CASTOR1 upstream of mTORC1 PDF

Robert A. Saxton, Lynne Chantranupong, Kevin E. Knockenhauer, Thomas Schwartz, David M. Sabatini - Nature, 2016
Cited by 328 OpenAlex

Sestrin2 is a leucine sensor for the mTORC1 pathway PDF

Rachel L. Wolfson, Lynne Chantranupong, Robert A. Saxton, Kuang Shen, Sonia M. Scaria et al. - Science, 2015
Cited by 1,249 OpenAlex

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. PDF

Shuyu Wang, Zhi-Yang Tsun, Rachel L. Wolfson, Kuang Shen, Gregory A. Wyant et al. - PubMed, 2015
Cited by 814 OpenAlex

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway PDF

Robert A. Saxton, Kevin E. Knockenhauer, Rachel L. Wolfson, Lynne Chantranupong, Michael E. Pacold et al. - Science, 2015
Cited by 443 OpenAlex

Nutrient-Sensing Mechanisms across Evolution PDF

Lynne Chantranupong, Rachel L. Wolfson, David M. Sabatini - Cell, 2015
Cited by 330 OpenAlex

The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1 PDF

Lynne Chantranupong, Rachel L. Wolfson, Jose M. Orozco, Robert A. Saxton, Sonia M. Scaria et al. - Cell Reports, 2014
Cited by 451 OpenAlex

Research Topics

PI3K/AKT/mTOR signaling in cancer (17) Polyamine Metabolism and Applications (11) Cellular transport and secretion (7) Amino Acid Enzymes and Metabolism (7) CRISPR and Genetic Engineering (6)

Frequent Co-Authors

DA
David M. Sabatini
12 joint publications
RA
Rachel L. Wolfson
6 joint publications
TI
Timothy C. Wang
5 joint publications
RO
Robert A. Saxton
5 joint publications
KU
Kuang Shen
5 joint publications
SO
Sonia M. Scaria
4 joint publications

Affiliations

Broad Institute
US 2018 - 2012
Howard Hughes Medical Institute
US 2024 - 2012
Harvard University
US 2024 - 2018
Laboratory of Molecular Genetics
PL 2010 - 2010
Allen Institute
US 2016 - 2013

External Profiles

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