Rebecca J. Howard

Oxleas NHS Foundation Trust GB

0000-0003-2049-3378

237

Publications

3,232

Citations

H-Index

i10-Index

2.31

2yr Mean Cite

Cite/Paper

Data combined from OpenAlex + Semantic Scholar. OA = OpenAlex S2 = Semantic Scholar

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Publication & Citation Trends

Most Cited Works

Shared structural mechanisms of general anaesthetics and benzodiazepines OA

Jeong Joo Kim, Anant Gharpure, Jinfeng Teng, Yuxuan Zhuang, Rebecca J. Howard +5 more

Nature 2020

373

The Structure of the APPBP1-UBA3-NEDD8-ATP Complex Reveals the Basis for Selective Ubiquitin-like Protein Activation by an E1 OA

Helen Walden, Michael Podgorski, Danny T. Huang, David W. Miller, Rebecca J. Howard +3 more

Molecular Cell 2003

276

Ring-Closing Metathesis of Olefinic Peptides: Design, Synthesis, and Structural Characterization of Macrocyclic Helical Peptides

Helen E. Blackwell, Jack Sadowsky, Rebecca J. Howard, Joshua N. Sampson, Jeffrey A. Chao +3 more

The Journal of Organic Chemistry 2001

222

Agonist Selectivity and Ion Permeation in the α3β4 Ganglionic Nicotinic Receptor OA

Anant Gharpure, Jinfeng Teng, Yuxuan Zhuang, Colleen Noviello, Richard M. Walsh +5 more

Neuron 2019

181

Structural Insight into KCNQ (Kv7) Channel Assembly and Channelopathy OA

Rebecca J. Howard, Kimberly A. Clark, James M. Holton, Daniel L. Minor

Neuron 2007

164

Publications

237 total

Mechanism of Alkaline Gating in a Pentameric Ion Channel

Emelia Karlsson, Ida Ygland, Anton Jansen, Jeffrey Plumley, E. Lindahl - bioRxiv, 2026

Cited by 0 Semantic Scholar

Several multiple sequence alignment perturbation methods enhance AlphaFold3 sampling of alternative protein states

Samuel Eriksson Lidbrink, Ivan Nissen, Jonathan Kenichi Ahrlind, Rebecca J. Howard, E. Lindahl - bioRxiv, 2026

Cited by 0 Semantic Scholar

Structure and dynamics of a multidomain ligand-gated ion channel revealed under acidic conditions OA

Olivia Andén, U. Rovšnik, M. Lycksell, Marc Delarue, Rebecca J. Howard - bioRxiv, 2026

Cited by 1 Semantic Scholar

Modeling cryo-EM structures in alternative states with generative AI and density-guided simulations

Tatiana Shugaeva, Rebecca J. Howard, Nandan Haloi, E. Lindahl - bioRxiv, 2025

Cited by 5 Semantic Scholar

Structural basis for activation and potentiation in a human α5β3 GABAA receptor OA

John Cowgill, Chen Fan, Jan Stayaert, Rebecca J. Howard, E. Lindahl - bioRxiv, 2025

Cited by 1 Semantic Scholar

A single main-chain hydrogen bond required to keep GABAA receptors closed

Cecilia M. Borghese, J. Galpin, Samuel Eriksson Lidbrink, Y. Zhuang, Netrang G. Desai - Nature Communications, 2025

Cited by 0 Semantic Scholar

Calcium stabilizes the flexible N-terminal domain of the bacterial ion channel DeCLIC

Chen Fan, M. Lycksell, Y. Zhuang, Rebecca J. Howard, E. Lindahl - Journal of structural biology: X, 2025

Cited by 0 Semantic Scholar

Constant-pH Molecular Dynamics Simulations of Closed and Open States of a Proton-gated Ion Channel OA

Anton Jansen, Paul Bauer, Rebecca J. Howard, Berk Hess, E. Lindahl - bioRxiv, 2025

Cited by 2 Semantic Scholar

Cryo-EM ligand building using AlphaFold3-like model and molecular dynamics

Nandan Haloi, Rebecca J. Howard, E. Lindahl - PLoS Comput. Biol., 2025

Cited by 3 Semantic Scholar

Structural insights into opposing actions of neurosteroids on GABAA receptors PDF

Dagimhiwat Legesse, Chen Fan, Jinfeng Teng, Yuxuan Zhuang, Rebecca J. Howard et al. - Nature Communications, 2023

Cited by 70 OpenAlex

Research Topics

Nicotinic Acetylcholine Receptors Study (83) Ion channel regulation and function (72) Neuroscience and Neuropharmacology Research (47) Receptor Mechanisms and Signaling (43) Electrochemical Analysis and Applications (31)

Frequent Co-Authors

Erik Lindahl

5 joint publications

Jinfeng Teng

4 joint publications

Ryan Hibbs

4 joint publications

R. Adron Harris

4 joint publications

Yuxuan Zhuang

3 joint publications

Colleen Noviello

3 joint publications

Affiliations

QB3

US 2007 - 2007

University of Southern California

US 2011 - 2011

California Institute of Technology

US 2001 - 2001

Oxleas NHS Foundation Trust

GB 2025 - 2025

National Institutes of Health

US 2024 - 1986

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Rebecca J. Howard

Publication & Citation Trends

Most Cited Works

Publications

Mechanism of Alkaline Gating in a Pentameric Ion Channel

Several multiple sequence alignment perturbation methods enhance AlphaFold3 sampling of alternative protein states

Structure and dynamics of a multidomain ligand-gated ion channel revealed under acidic conditions OA

Modeling cryo-EM structures in alternative states with generative AI and density-guided simulations

Structural basis for activation and potentiation in a human α5β3 GABAA receptor OA

A single main-chain hydrogen bond required to keep GABAA receptors closed

Calcium stabilizes the flexible N-terminal domain of the bacterial ion channel DeCLIC

Constant-pH Molecular Dynamics Simulations of Closed and Open States of a Proton-gated Ion Channel OA

Cryo-EM ligand building using AlphaFold3-like model and molecular dynamics

Structural insights into opposing actions of neurosteroids on GABAA receptors PDF

Research Topics

Frequent Co-Authors

Affiliations

External Profiles

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