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Patrick J. Lupardus

Joint Center for Structural Genomics US

ORCID iD 0000-0002-8662-074X
123
Publications
7,864
Citations
41
H-Index
58
i10-Index
3.0
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Most Cited Works

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
Mahesh Yadav, Suchit Jhunjhunwala, Qui Phung, Patrick J. Lupardus, Joshua Tanguay +9 more
Nature 2014
1,179
Novel antibody–antibiotic conjugate eliminates intracellular S. aureus
Sophie M. Lehar, Thomas H. Pillow, Min Xu, Leanna R. Staben, Kimberly K. Kajihara +27 more
Nature 2015
821
Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability OA
Benjamin Lauffer, Robert Mintzer, Rina Fong, Susmith Mukund, Christine Tam +14 more
Journal of Biological Chemistry 2013
406
Kinase inhibition in autoimmunity and inflammation OA
Ali A. Zarrin, Katherine Bao, Patrick J. Lupardus, Domagoj Vucic
Nature Reviews Drug Discovery 2020
405
Structural Biology of Shared Cytokine Receptors
Xinquan Wang, Patrick J. Lupardus, Sherry L. LaPorte, K. Christopher García
Annual Review of Immunology 2007
396

Publications

123 total

Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation PDF

Caleb R. Glassman, Naotaka Tsutsumi, Robert A. Saxton, Patrick J. Lupardus, Kevin M. Jude et al. - Science, 2022
Cited by 167 OpenAlex

Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells PDF

Caleb R. Glassman, Yamuna Kalyani Mathiharan, Kevin M. Jude, Leon Su, Ouliana Panova et al. - Cell, 2021
Cited by 175 OpenAlex

Kinase inhibition in autoimmunity and inflammation PDF

Ali A. Zarrin, Katherine Bao, Patrick J. Lupardus, Domagoj Vucic - Nature Reviews Drug Discovery, 2020
Cited by 405 OpenAlex

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function PDF

David H. Hackos, Patrick J. Lupardus, Teddy Grand, Yelin Chen, Tzu-Ming Wang et al. - Neuron, 2016
Cited by 171 OpenAlex

Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

Sophie M. Lehar, Thomas H. Pillow, Min Xu, Leanna R. Staben, Kimberly K. Kajihara et al. - Nature, 2015
Cited by 821 OpenAlex

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

Mahesh Yadav, Suchit Jhunjhunwala, Qui Phung, Patrick J. Lupardus, Joshua Tanguay et al. - Nature, 2014
Cited by 1,179 OpenAlex

Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition PDF

Patrick J. Lupardus, Mark Ultsch, Heidi J.A. Wallweber, Pawan Bir Kohli, Adam R. Johnson et al. - Proceedings of the National Academy of Sciences, 2014
Cited by 218 OpenAlex

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2 PDF

Heidi J.A. Wallweber, Christine Tam, Yvonne Franke, Melissa A. Starovasnik, Patrick J. Lupardus - Nature Structural & Molecular Biology, 2014
Cited by 146 OpenAlex

Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability PDF

Benjamin Lauffer, Robert Mintzer, Rina Fong, Susmith Mukund, Christine Tam et al. - Journal of Biological Chemistry, 2013
Cited by 406 OpenAlex

An In Vivo Human-Plasmablast Enrichment Technique Allows Rapid Identification of Therapeutic Influenza A Antibodies PDF

Gerald Nakamura, Ning Chai, Summer Park, Nancy Chiang, Zhonghua Lin et al. - Cell Host & Microbe, 2013
Cited by 177 OpenAlex

Research Topics

Cytokine Signaling Pathways and Interactions (33) Monoclonal and Polyclonal Antibodies Research (19) Immune Cell Function and Interaction (16) DNA Repair Mechanisms (12) CAR-T cell therapy research (11)

Frequent Co-Authors

K.
K. Christopher García
5 joint publications
RI
Rina Fong
3 joint publications
HE
Heidi J.A. Wallweber
3 joint publications
ZO
Zora Modrušan
2 joint publications
JA
Janice Kim
2 joint publications
SU
Summer Park
2 joint publications

Affiliations

Howard Hughes Medical Institute
US 2012 - 2007
University of Wisconsin–Madison
US 2000 - 1999
GTx (United States)
US 2022 - 2022
Ansys (United States)
US 2022 - 2022
Stratford University
US 2011 - 2011

External Profiles

OpenAlex Profile Search Semantic Scholar ORCID Profile Google Scholar

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