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Clare Hughes

Cardiff University GB

ORCID iD 0000-0003-4726-5877
185
Publications
7,775
Citations
47
H-Index
79
i10-Index
0
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Publications

182 total

The role of synovial macrophages and macrophage‐produced mediators in driving inflammatory and destructive responses in osteoarthritis PDF

Jan Bondeson, Arjen B. Blom, S.D. Wainwright, Clare Hughes, Bruce Caterson et al. - Arthritis & Rheumatism, 2010
Cited by 420 OpenAlex

The regulation of the ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review.

Jan Bondeson, Sami Wainwright, Clare Hughes, Bruce Caterson - PubMed, 2008
Cited by 188 OpenAlex

Proteolytic Activities of Human ADAMTS-5 PDF

Christi M. Gendron, Masahide Kashiwagi, Ngee Han Lim, Jan J. Enghild, Ida B. Thøgersen et al. - Journal of Biological Chemistry, 2007
Cited by 251 OpenAlex

The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis PDF

Jan Bondeson, S.D. Wainwright, Sarah N. Lauder, Nick Amos, Clare Hughes - Arthritis Research & Therapy, 2006
Cited by 513 OpenAlex

The Role of Human HtrA1 in Arthritic Disease PDF

Sandra Grau, Peter J. Richards, Briedgeen Kerr, Clare Hughes, Bruce Caterson et al. - Journal of Biological Chemistry, 2005
Cited by 288 OpenAlex

Altered Proteolytic Activities of ADAMTS-4 Expressed by C-terminal Processing PDF

Masahide Kashiwagi, Jan J. Enghild, Christi M. Gendron, Clare Hughes, Bruce Caterson et al. - Journal of Biological Chemistry, 2004
Cited by 403 OpenAlex

Pathologic indicators of degradation and inflammation in human osteoarthritic cartilage are abrogated by exposure to n‐3 fatty acids

C Curtis, Sarah Rees, Christopher B. Little, Carl R. Flannery, Clare Hughes et al. - Arthritis & Rheumatism, 2002
Cited by 176 OpenAlex

Mechanisms involved in cartilage proteoglycan catabolism

Bruce Caterson, Carl R. Flannery, Clare Hughes, Christopher B. Little - Matrix Biology, 2000
Cited by 287 OpenAlex

n-3 Fatty Acids Specifically Modulate Catabolic Factors Involved in Articular Cartilage Degradation PDF

C Curtis, Clare Hughes, Carl R. Flannery, Christopher B. Little, John L. Harwood et al. - Journal of Biological Chemistry, 2000
Cited by 272 OpenAlex

Articular Cartilage Superficial Zone Protein (SZP) Is Homologous to Megakaryocyte Stimulating Factor Precursor and Is a Multifunctional Proteoglycan with Potential Growth-Promoting, Cytoprotective, and Lubricating Properties in Cartilage Metabolism

Carl R. Flannery, Clare Hughes, Barbara L. Schumacher, Debbie Tudor, Margaret B. Aydelotte et al. - Biochemical and Biophysical Research Communications, 1999
Cited by 355 OpenAlex

Research Topics

Osteoarthritis Treatment and Mechanisms (72) Proteoglycans and glycosaminoglycans research (42) Cell Adhesion Molecules Research (34) Protease and Inhibitor Mechanisms (32) Monoclonal and Polyclonal Antibodies Research (25)

Affiliations

University of North Carolina at Chapel Hill
US 1992 - 1992
Leeds General Infirmary
GB 2004 - 2004
Trinity Health
US 2023 - 2023
University Hospitals Birmingham NHS Foundation Trust
GB 2024 - 2024
St Thomas' Hospital
GB 2002 - 2002

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