Publication & Citation Trends
Most Cited Works
Publications
27 total
Structure activity relationship studies of tricyclic bispyran sulfone γ-secretase inhibitors.
Cited by 12
Semantic Scholar
In Vivo Characterization of a Novel γ-Secretase Inhibitor SCH 697466 in Rodents and Investigation of Strategies for Managing Notch-Related Side Effects OA
Cited by 6
Semantic Scholar
Efficient synthesis and reaction pathway studies of novel fused morpholine oxadiazolines for use as gamma secretase modulators
Cited by 13
Semantic Scholar
Cyclic Hydroxyamidines as Amide Isosteres: Discovery of Oxadiazolines and Oxadiazines as Potent and Highly Efficacious γ-Secretase Modulators in Vivo PDF
Cited by 52
OpenAlex
Identification of Presenilin 1-Selective γ-Secretase Inhibitors with Reconstituted γ-Secretase Complexes
Cited by 34
OpenAlex
Tetracyclic sulfones as potent gamma-secretase inhibitors: synthesis and structure-activity relationship studies.
Cited by 9
Semantic Scholar
Discovery of 2,4,6-trisubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors PDF
Cited by 25
OpenAlex
Small conformationally restricted piperidine N-arylsulfonamides as orally active γ-secretase inhibitors PDF
Cited by 25
OpenAlex
Research Topics
Cholinesterase and Neurodegenerative Diseases
(8)
Computational Drug Discovery Methods
(7)
Alzheimer's disease research and treatments
(6)
Chemical Synthesis and Analysis
(5)
Synthetic Organic Chemistry Methods
(4)
Frequent Co-Authors
Affiliations
Merck & Co., Inc., Rahway, NJ, USA (United States)
AGCO (United Kingdom)
AIL Research (United States)
University of Rochester