Tsutomu Shimada

Kanazawa University JP

0000-0003-2552-4348

391

Publications

23,681

Citations

H-Index

243

i10-Index

0.5

2yr Mean Cite

Cite/Paper

Data combined from OpenAlex + Semantic Scholar. OA = OpenAlex S2 = Semantic Scholar

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Publication & Citation Trends

Most Cited Works

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura, Yukiharu Inui, F. Peter Guengerich

Journal of Pharmacology and Experimental Therapeutics 1994

2,781

Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes

F. Peter Guengerich, Tsutomu Shimada

Chemical Research in Toxicology 1991

995

Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.

Tsutomu Shimada, Carrie L. Hayes, Hiroshi Yamazaki, Shantu Amin, Stephen S. Hecht +2 more

PubMed 1996

795

Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and1B1 OA

Tsutomu Shimada, Yoshiaki Fujii‐Kuriyama

Cancer Science 2004

793

Xenobiotic-Metabolizing Enzymes Involved in Activation and Detoxification of Carcinogenic Polycyclic Aromatic Hydrocarbons

Tsutomu Shimada

Drug Metabolism and Pharmacokinetics 2006

588

Publications

391 total

Xenobiotic-Metabolizing Enzymes Involved in Activation and Detoxification of Carcinogenic Polycyclic Aromatic Hydrocarbons

Tsutomu Shimada - Drug Metabolism and Pharmacokinetics, 2006

Cited by 588 OpenAlex

Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and1B1 PDF

Tsutomu Shimada, Yoshiaki Fujii‐Kuriyama - Cancer Science, 2004

Cited by 793 OpenAlex

Catalytic properties of polymorphic human cytochrome P450 1B1 variants PDF

Tsutomu Shimada - Carcinogenesis, 1999

Cited by 274 OpenAlex

Activation and detoxication of aflatoxin B1

F. Peter Guengerich, William W. Johnson, Tsutomu Shimada, Yune‐Fang Ueng, Hiroshi Yamazaki et al. - Mutation research. Fundamental and molecular mechanisms of mutagenesis, 1998

Cited by 342 OpenAlex

Activation of procarcinogens by human cytochrome P450 enzymes

F. Peter Guengerich, Tsutomu Shimada - Mutation research. Fundamental and molecular mechanisms of mutagenesis, 1998

Cited by 265 OpenAlex

Synthesis of 1,3-Selenazoles and 2-Imidazolin-5-selones from Isoselenocyanates and Isocyanides.

H. Maeda, N. Kambe, N. Sonoda, Shin‐ichi Fujiwara, S. Tsutomu - Unknown Venue, 1998

Cited by 0 Semantic Scholar

Progesterone and Testosterone Hydroxylation by Cytochromes P450 2C19, 2C9, and 3A4 in Human Liver Microsomes

Hiroshi Yamazaki, Tsutomu Shimada - Archives of Biochemistry and Biophysics, 1997

Cited by 309 OpenAlex

Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.

Tsutomu Shimada, Carrie L. Hayes, Hiroshi Yamazaki, Shantu Amin, Stephen S. Hecht et al. - PubMed, 1996

Cited by 795 OpenAlex

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura, Yukiharu Inui, F. Peter Guengerich - Journal of Pharmacology and Experimental Therapeutics, 1994

Cited by 2,781 OpenAlex

Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of <i>N</i>-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

Hiroshi Yamazaki, Yukiharu Inui, Chul‐Ho Yun, F. Peter Guengerich, Tsutomu Shimada - Carcinogenesis, 1992

Cited by 397 OpenAlex

Research Topics

Pharmacogenetics and Drug Metabolism (167) Carcinogens and Genotoxicity Assessment (63) Drug Transport and Resistance Mechanisms (63) Eicosanoids and Hypertension Pharmacology (25) Chemical Reactions and Isotopes (25)

Frequent Co-Authors

F. Peter Guengerich

8 joint publications

Hiroshi Yamazaki

5 joint publications

Yukiharu Inui

2 joint publications

Chul‐Ho Yun

2 joint publications

Mayumi Mimura

1 joint publication

Carrie L. Hayes

1 joint publication

Affiliations

Kanazawa University

JP 2025 - 2005

Kurume University

JP 1984 - 1984

Tulane University

US 1998 - 1998

Aoyama Gakuin University

JP 1995 - 1995

Alfred I. duPont Hospital for Children

US 2015 - 2013

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Tsutomu Shimada

Publication & Citation Trends

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