Publication & Citation Trends
Most Cited Works
Publications
57 total
Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors PDF
Cited by 65
OpenAlex
Drug Targeting to Monocytes and Macrophages Using Esterase-Sensitive Chemical Motifs
Cited by 69
OpenAlex
Discovery of 2-(6-{[(6-Fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-<i>N</i>-hydroxypyrimidine-5-carboxamide (CHR-3996), a Class I Selective Orally Active Histone Deacetylase Inhibitor PDF
Cited by 83
OpenAlex
Phase I/II Clinical Study of Tosedostat, an Inhibitor of Aminopeptidases, in Patients With Acute Myeloid Leukemia and Myelodysplasia
Cited by 74
OpenAlex
CHR-2797: An Antiproliferative Aminopeptidase Inhibitor that Leads to Amino Acid Deprivation in Human Leukemic Cells PDF
Cited by 117
OpenAlex
A matrix metalloproteinase inhibitor, batimastat, retards the development of osteolytic bone metastases by MDA-MB-231 human breast cancer cells in Balb C nu/nu mice
Cited by 59
OpenAlex
Batimastat, a synthetic inhibitor of matrix metalloproteinases, potentiates the antitumor activity of cisplatin in ovarian carcinoma xenografts.
Cited by 85
OpenAlex
Research Topics
Peptidase Inhibition and Analysis
(27)
Histone Deacetylase Inhibitors Research
(19)
Protease and Inhibitor Mechanisms
(9)
Protein Degradation and Inhibitors
(8)
Signaling Pathways in Disease
(6)
Frequent Co-Authors
Affiliations
National Institutes of Health
Churchill Hospital
Cancer Research UK
University of Manchester
Yale University