D. E. Schmechel

New York State Department of Health US

Publications

27,091

Citations

H-Index

i10-Index

2yr Mean Cite

Cite/Paper

Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar

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Publication & Citation Trends

Most Cited Works

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel, P. C. Gaskell +4 more

Science 1993

9,399

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. OA

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel, M. A. Pericak‐Vance, Jan J. Enghild +2 more

Proceedings of the National Academy of Sciences 1993

4,273

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease OA

Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel, Peter St George‐Hyslop, Jeffery M. Vance +9 more

Neurology 1993

3,800

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

Elizabeth H. Corder, Ann M. Saunders, Neil Risch, Warren J. Strittmatter, D. E. Schmechel +9 more

Nature Genetics 1994

1,912

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. OA

D. E. Schmechel, Ann M. Saunders, Warren J. Strittmatter, Barbara J. Crain, Christine M. Hulette +4 more

Proceedings of the National Academy of Sciences 1993

1,524

Publications

50 total

Apolipoprotein E allele-dependent pathogenesis: A model for age-related retinal degeneration

Goldis Malek, Lincoln V. Johnson, Brian E. Mace, Peter Saloupis, D. E. Schmechel et al. - Proceedings of the National Academy of Sciences, 2005

Cited by 281 OpenAlex

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

Elizabeth H. Corder, Ann M. Saunders, Neil Risch, Warren J. Strittmatter, D. E. Schmechel et al. - Nature Genetics, 1994

Cited by 1,912 OpenAlex

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. OA

Warren J. Strittmatter, Ann M. Saunders, Michel Goedert, Karl H. Weisgraber, Li Dong et al. - Proceedings of the National Academy of Sciences, 1994

Cited by 468 OpenAlex

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. PDF

David A. Sanan, Karl H. Weisgraber, Stephen J. Russell, Robert W. Mahley, David Huang et al. - Journal of Clinical Investigation, 1994

Cited by 415 OpenAlex

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel, P. C. Gaskell et al. - Science, 1993

Cited by 9,399 OpenAlex

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. PDF

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel, M. A. Pericak‐Vance, Jan J. Enghild et al. - Proceedings of the National Academy of Sciences, 1993

Cited by 4,273 OpenAlex

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease PDF

Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel, Peter St George‐Hyslop, Jeffery M. Vance et al. - Neurology, 1993

Cited by 3,800 OpenAlex

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. PDF

D. E. Schmechel, Ann M. Saunders, Warren J. Strittmatter, Barbara J. Crain, Christine M. Hulette et al. - Proceedings of the National Academy of Sciences, 1993

Cited by 1,524 OpenAlex

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. OA

Warren J. Strittmatter, Karl H. Weisgraber, Daoyuan Huang, Li Dong, Guy S. Salvesen et al. - Proceedings of the National Academy of Sciences, 1993

Cited by 1,360 OpenAlex

Apolipoprotein E &isin;4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases

Ann M. Saunders, Allen D. Roses, Jeffery M. Vance, Kenneth C. Dole, Warren J. Strittmatter et al. - The Lancet, 1993

Cited by 500 OpenAlex

Research Topics

Alzheimer's disease research and treatments (21) Neuroscience and Neuropharmacology Research (7) Dementia and Cognitive Impairment Research (6) Bioinformatics and Genomic Networks (6) S100 Proteins and Annexins (6)

Frequent Co-Authors

Ann M. Saunders

9 joint publications

Warren J. Strittmatter

8 joint publications

Allen D. Roses

8 joint publications

Jeffery M. Vance

5 joint publications

Dmitry Goldgaber

4 joint publications

Karl H. Weisgraber

3 joint publications

Affiliations

New York State Department of Health

US 2015 - 2015

Gladstone Institutes

US 1994 - 1994

University of California, Santa Barbara

US 2005 - 2005

Duke University

US 2003 - 1985

East Carolina University

US 2001 - 2001

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D. E. Schmechel

Publication & Citation Trends

Most Cited Works

Publications

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. OA

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. OA

Research Topics

Frequent Co-Authors

Affiliations

External Profiles

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