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LR

Lionel Rougé

Denali Therapeutics (United States) US

ORCID iD 0000-0002-7953-5803
93
Publications
3,059
Citations
25
H-Index
32
i10-Index
16.6
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex + Semantic Scholar. OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Publications

93 total

Discovery and characterization of potent macrocycle inhibitors of ubiquitin-specific protease-7.

Rafael Miranda, Francesca Anson, Shannon T. Smith, M. Ultsch, Connie A. Tenorio - Structure, 2025
Cited by 2 Semantic Scholar

Structural insights into mechanisms underlying stabilization of a lysosomal enzyme through protein engineering

Jennifer E. Kung, Ahlam N. Qerqez, Tianao Yuan, L. Rougé, Annalee W. Nguyen - Structural Dynamics, 2025
Cited by 0 Semantic Scholar

Large-scale single-molecule analysis of tau proteoforms

J. Joly, V. Budamagunta, Z. Zhang, B. Nortman, M. Jouzi - bioRxiv, 2025
Cited by 1 Semantic Scholar

Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab PDF

Lionel Rougé, Nancy Chiang, Micah Steffek, Christine Kugel, Tristan I. Croll et al. - Science, 2020
Cited by 193 OpenAlex

Optimized arylomycins are a new class of Gram-negative antibiotics

Peter A. Smith, Michael F. T. Koehler, Hany S. Girgis, Donghong Yan, Yongsheng Chen et al. - Nature, 2018
Cited by 354 OpenAlex

USP7 small-molecule inhibitors interfere with ubiquitin binding PDF

Lorna Kategaya, Paola Di Lello, Lionel Rougé, Richard Pastor, Kevin Clark et al. - Nature, 2017
Cited by 336 OpenAlex

Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell–cell adhesion and signaling mechanism that requires <i>cis-trans</i> receptor clustering PDF

Katharina Stengel, Kristin Harden-Bowles, Xin Yu, Lionel Rougé, Jianping Yin et al. - Proceedings of the National Academy of Sciences, 2012
Cited by 212 OpenAlex

A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo

Jasvinder K. Atwal, Yongmei Chen, Cecilia Chiu, Deborah L. Mortensen, William J. Meilandt et al. - Science Translational Medicine, 2011
Cited by 277 OpenAlex

Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer PDF

Daniel P. Sutherlin, Linda Bao, Megan Berry, Georgette M. Castanedo, Irina Chuckowree et al. - Journal of Medicinal Chemistry, 2011
Cited by 217 OpenAlex

Wnt Antagonists Bind through a Short Peptide to the First β-Propeller Domain of LRP5/6 PDF

Eric Bourhis, Weiru Wang, Christine Tam, Ji‐Young Hwang, Yingnan Zhang et al. - Structure, 2011
Cited by 168 OpenAlex

Research Topics

French Urban and Social Studies (25) Ubiquitin and proteasome pathways (13) Aging, Elder Care, and Social Issues (13) Cancer-related Molecular Pathways (12) Agriculture and Rural Development Research (9)

Affiliations

Novartis (Switzerland)
CH 2012 - 2012
Centre National de la Recherche Scientifique
FR 2017 - 2007
Johns Hopkins University
US 2006 - 2006
University of California, San Francisco
US 2012 - 2012
Genentech
2013 - 2013

External Profiles

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