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RP

Richard Pastor

Independent Researcher

25
Publications
707
Citations
9
H-Index
9
i10-Index
0
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex + Semantic Scholar. OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Most Cited Works

USP7 small-molecule inhibitors interfere with ubiquitin binding OA
Lorna Kategaya, Paola Di Lello, Lionel Rougé, Richard Pastor, Kevin Clark +39 more
Nature 2017
336
Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637) OA
Alexander M. Taylor, Alexandre Côté, Michael C. Hewitt, Richard Pastor, Yves Leblanc +39 more
ACS Medicinal Chemistry Letters 2016
112
Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques OA
Paola Di Lello, Richard Pastor, Jeremy Murray, Robert A. Blake, Frederick Cohen +11 more
Journal of Medicinal Chemistry 2017
87
2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitors OA
Michael Siu, Richard Pastor, Wendy Liu, Kathy Barrett, Megan Berry +20 more
Bioorganic & Medicinal Chemistry Letters 2013
46
Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2) OA
Zhonghua Pei, Rohan Mendonca, Lewis Gazzard, Richard Pastor, Leanne Goon +11 more
ACS Medicinal Chemistry Letters 2018
40

Publications

25 total

CCDC 2076981: Experimental Crystal Structure Determination PDF

Brendan T. Parr, Richard Pastor, Benjamin D. Sellers, Zhonghua Pei, Firoz A. Jaipuri et al. - The Cambridge Structural Database, 2021
Cited by 0 OpenAlex

CCDC 2076977: Experimental Crystal Structure Determination PDF

Brendan T. Parr, Richard Pastor, Benjamin D. Sellers, Zhonghua Pei, Firoz A. Jaipuri et al. - The Cambridge Structural Database, 2021
Cited by 0 OpenAlex

Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors PDF

Brendan T. Parr, Richard Pastor, Benjamin D. Sellers, Zhonghua Pei, Firoz A. Jaipuri et al. - ACS Medicinal Chemistry Letters, 2020
Cited by 28 OpenAlex

Optimization of globomycin analogs as novel gram-negative antibiotics

Keira Garland, Homer Pantua, M. Braun, Daniel J. Burdick, Georgette M. Castanedo et al. - Bioorganic & Medicinal Chemistry Letters, 2020
Cited by 22 OpenAlex

Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2) PDF

Zhonghua Pei, Rohan Mendonca, Lewis Gazzard, Richard Pastor, Leanne Goon et al. - ACS Medicinal Chemistry Letters, 2018
Cited by 40 OpenAlex

Abstract SY23-03: Development and mechanistic characterization of USP7 deubiquitinase inhibitors

Ingrid E. Wertz, Lorna Kategaya, Paola Di Lello, Lionel Rougé, Richard Pastor et al. - Cancer Research, 2018
Cited by 0 OpenAlex

USP7 small-molecule inhibitors interfere with ubiquitin binding PDF

Lorna Kategaya, Paola Di Lello, Lionel Rougé, Richard Pastor, Kevin Clark et al. - Nature, 2017
Cited by 336 OpenAlex

Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques PDF

Paola Di Lello, Richard Pastor, Jeremy Murray, Robert A. Blake, Frederick Cohen et al. - Journal of Medicinal Chemistry, 2017
Cited by 87 OpenAlex

Abstract B23: Crucial deubiquitinases in cancer cell survival

Lorna Kategaya, Trinna Cuellar, Ben Haley, Jinfeng Liu, Andy D. Tran et al. - Clinical Cancer Research, 2017
Cited by 0 OpenAlex

1 USP 7 Small Molecule Inhibitors Interfere with Ubiquitin Binding 1 2

L. Kategaya, P. Lello, L. Rougé, Richard M Pastor, K. Clark - Unknown Venue, 2017
Cited by 0 Semantic Scholar

Research Topics

Crystallization and Solubility Studies (10) X-ray Diffraction in Crystallography (10) Cancer-related Molecular Pathways (4) Ubiquitin and proteasome pathways (4) Tryptophan and brain disorders (3)

Frequent Co-Authors

VI
Vickie Tsui
6 joint publications
JE
Jeremy Murray
5 joint publications
LO
Lorna Kategaya
4 joint publications
PA
Paola Di Lello
4 joint publications
CH
Chudi Ndubaku
4 joint publications
RO
Robert A. Blake
4 joint publications

Affiliations

Toxicologie, Pharmacologie et Signalisation Cellulaire
FR 2018 - 2018
Université Bourgogne Franche-Comté
FR 2012 - 2012
Gilead Sciences (United States)
US 2012 - 2008

External Profiles

OpenAlex Profile Semantic Scholar Profile Google Scholar

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